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Showing 1 results for Bagheri Matak
Mrs Sareh Bagheri Matak, Dr Elham Askari, Dr Sara Motamed,
Volume 16, Issue 2 (8-2025)
Abstract
Leukemia is one of the most common and dangerous types of cancer in the world. In many cases, the disease is curable if detected in its early stages. One of the effective tools for early detection is the analysis of microarray data, which measures the expression of thousands of genes simultaneously. However, the large volume of features and the presence of noise make the analysis process complex and time-consuming. Therefore, the selection of effective genes plays a key role in increasing the accuracy and reducing the computational cost of learning models. In this paper, a two-step hybrid approach is presented for feature selection and classification of leukemia types. In the first step, the features are filtered using the mutual information criterion and the genes with the highest correlation with the disease label are selected. In the second step, the XGBoost model is used to rank and stably select the features to identify the genes that are most important in different iterations. In the final stage, classification will be performed using the temporal fusion transformer method, which allows for fast and efficient learning of complex patterns among selected genes. Experimental results on real microarray datasets show that the proposed method outperforms the baseline methods with an accuracy of 99.2% and has been able to identify key genes effective in differentiating leukemia types by effectively reducing the data dimensions.
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