‎In this paper, using the idea of convexificators, we study boundedness and nonemptiness of Lagrange multipliers satisfying the first order necessary conditions. We consider a class of nons- mooth fractional programming problems with equality, inequality constraints and an arbitrary set constraint. Within this context, define generalized Mangasarian-Fromovitz constraint qualification and show that the constraint qualification are necessary and suficient conditions for the Karush- Kuhn-Tucker(KKT) multipliers set to be nonempty and bounded.